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Sleep deprivation and circadian disruption have been associated with impaired glucose tolerance and altered appetite-regulating hormones
In a recent study, administration of exendin-4, a long-acting GLP-1RA, stimulated -cell proliferation in juvenile human islets by inducing gene expressions of calcineurin/nuclear factor of activated T cells (NFAT) signaling, a proliferating factor such as NFATC1, and a cell cycle regulator such as cyclin A1 [57]
Deacon et al The Glucagon-Like Peptides Endo Rev
Pevec D, Novinscak T, Brcic L, et al
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